Two sample MR report
WBSCR27_Dendritic Cell (DC) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.2146887 | 0.2686871 | 0.5080872 |
| Weighted median | 4 | 0.0628498 | 0.0120310 | 0.0000002 |
| Inverse variance weighted | 4 | 0.0612071 | 0.0087768 | 0.0000000 |
| Simple mode | 4 | 0.0655095 | 0.0153625 | 0.0236598 |
| Weighted mode | 4 | 0.0654460 | 0.0158122 | 0.0256041 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0650112 | 2 | 0.9680170 |
| Inverse variance weighted | 0.3916609 | 3 | 0.9419597 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1487135 | 0.2602012 | 0.6253069 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 7.73e-05 | 1e-07 | TRUE | 0.4223157 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
